Louisville football hosts the Stanford Cardinal at L&N Federal Credit Union Stadium on Saturday, October 31st, kicking off at 3:15 pm E.T. with a 22.5-point spread favoring the home team. FanDuel lists the over/under at 60.5 points, while ESPN Analytics pegs the Cardinals’ win probability at 97.2 percent as both programs look to extend active winning streaks.
The matchup marks the second meeting in program history. In their previous encounter during the 2024 season, Louisville traveled to Stanford Stadium where Stanford won 38-35, leaving UofL searching for its first win against Stanford.
Both teams enter Week 9 riding momentum. Stanford secured an impressive win over North Carolina State, while Louisville picked up victories against Florida State and Syracuse. Sitting at 4-3 and fifth in the ACC standings, the Cardinals aim to start a late-season surge this afternoon. Stanford enters the contest with a 4-4 record.
Betting markets reflect heavy confidence in the home side. FanDuel lists Louisville’s moneyline at -2000, with Stanford priced at +1000. Despite the three-touchdown spread, analytical models and oddsmakers anticipate a comfortable margin for the Cardinals by the final whistle.
Louisville will be without receiver Lawayne McCoy for the afternoon showdown, though the rest of the roster appears largely healthy. On the other side, Stanford relies heavily on running back Micah Ford. Ford ranks second in the conference with 679 rushing yards on 136 carries, alongside eight touchdowns. Slowing him down remains a primary defensive priority for a Louisville squad looking to exploit defensive gaps in the second half.
The broadcast will air live on the ACC Network, with streaming available through fuboTV. Game odds remain subject to periodic updates.