Scientists profile genome-wide exon deletion to study gene function in stem cells
Researchers have developed new methods and vectors to profile genome-wide exon deletions, providing a system to study gene function in stem cells. By utilizing CRISPR-based technologies, including Cas9 and Cas12a variants, scientists have created experimental pipelines to target and remove specific exons for functional analysis. CRISPR-Mediated Genomic Editing with CHyMErA Cell Lines Experimental Framework and … Read more